Reishi mushrooms, also known as Ganoderma lucidum, have been used for medicinal purposes for thousands of years in traditional Chinese medicine. Recent scientific studies have confirmed that this mushroom is a potent anti-inflammatory agent. Inflammation is a natural immune response to injury or infection, but chronic inflammation can lead to a variety of health problems, including heart disease, diabetes, and arthritis. Here is a look at the scientific studies on the anti-inflammatory properties of reishi mushrooms.
In a study published in the International Journal of Molecular Sciences, researchers investigated the anti-inflammatory effects of reishi mushroom extracts on human skin cells. The results showed that reishi mushroom extracts significantly reduced inflammation in these cells, indicating potential benefits for skin health.
Another study published in the Journal of Medicinal Food examined the effects of reishi mushroom extract on inflammation in rats. The researchers induced inflammation by injecting carrageenan, a substance that causes swelling and inflammation, into the rats' paws. The rats were then treated with reishi mushroom extract, and the results showed a significant reduction in inflammation compared to the control group.
Research has also found that reishi mushrooms may have anti-inflammatory effects on the brain. In a study published in the Journal of Neuroinflammation, researchers investigated the effects of reishi mushroom extracts on inflammation in the brains of mice. The results showed that reishi mushroom extracts reduced inflammation and improved cognitive function in the mice.
Another study published in the Journal of Ethnopharmacology examined the effects of reishi mushroom extracts on inflammation in the liver. The researchers induced liver damage and inflammation in rats by injecting carbon tetrachloride, a toxic chemical. The results showed that reishi mushroom extracts reduced inflammation and protected the liver from damage.
The anti-inflammatory effects of reishi mushrooms are thought to be due to their high content of polysaccharides and triterpenes. These compounds have been shown to inhibit the production of pro-inflammatory cytokines and chemokines, which are molecules that promote inflammation in the body.
Overall, the scientific studies on the anti-inflammatory properties of reishi mushrooms suggest that they may be a beneficial addition to an anti-inflammatory diet. More research is needed to fully understand the mechanisms behind their anti-inflammatory effects and to determine the optimal dosage for therapeutic use.
In addition to their anti-inflammatory properties, reishi mushrooms have been found to have a variety of other health benefits, including immune system support, antioxidant activity, and anti-cancer properties. They are also rich in vitamins and minerals, making them a nutritious addition to any diet.
It is important to note that while reishi mushrooms are generally considered safe, they can interact with certain medications and may cause side effects in some people. It is always best to consult with a healthcare provider before adding any new supplements to your diet.
In conclusion, the scientific studies on the anti-inflammatory properties of reishi mushrooms suggest that they may have potential benefits for a variety of health conditions. While more research is needed, the evidence so far supports the use of reishi mushrooms as a natural anti-inflammatory agent.
Sources:
Wachtel-Galor, S., et al. "Ganoderma lucidum (Lingzhi or Reishi): A Medicinal Mushroom." Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition., U.S. National Library of Medicine, 1 Jan. 1970, www.ncbi.nlm.nih.gov/books/NBK92757/
Chang, Y. H., et al. "Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota." Nature Communications, vol. 6, no. 1, 2015, doi:10.1038/ncomms7345.
Chen, S. C., et al. "Polysaccharides of Ganoderma lucidum alter cell immunophenotypic expression and enhance CD56+ NK-cell cytotoxicity in cord blood." Bioorganic & Medicinal Chemistry, vol. 17, no. 21, 2009, pp. 7831–7840., doi:10.1016/j.bmc.2009.08.003.
Lin, Y. L., et al. "Anti-Inflammatory and Radical Scavenging Properties of Polysaccharides from Ganoderma lucidum." International Journal of Molecular Sciences, vol. 15, no. 5, 2014, pp. 7502–7513., doi:10.3390/ijms15057502.
Zhang, J., et al. "The Anti-Inflammatory Effects of Ganoderma lucidum Triterpenoid in a Model of Dextran Sulfate Sodium-Induced Colitis." BioMed Research International, vol. 2018, 2018, pp. 1–9., doi:10.1155/2018/1803756.